Customized partially covered biodegradable stent for anastomotic leakage after esophagojejunostomy.

stent for anastomotic leakage after esophagojejunostomy A 73-year-old man underwent a total gastrectomy plus splenectomy for a gastric adenocarcinoma (T3N1M0). At the early postoperative stage, the patient presented an esophagojejunostomy leak (>1cm diameter;●" Fig.1a). Medical management and endoscopic treatment were considered first. A customized, partially covered biodegradable stent (●" Fig.1b) (Ella Stent; ELLA-CS, Hradec Kralove, Czech Republic; diameter 31/25/31mm, length 110mm) was successfully placed under fluoroscopic and endoscopic guidance 5 weeks after surgery. At follow-up with endoscopic monitoring at 4 days (●" Fig.1c,d), 20 days, and 2 months (●" Fig.1e) after stent placement, adherence of each noncovered stentend (proximallyanddistally) was observed, as was an intrastent fold causing partial obstruction of the stent’s lumen. Balloon dilation up to 20mm was performed without incident, improving the luminal patency of the stent. The patient felt progressively better, and oral feeding was started after barium transit had shown nonleakage of the lumen with resolution of the dehiscence (●" Fig.1 f). Upper endoscopy 14 weeks later confirmed the total disappearance of the biodegradable stent and sealing of the anastomotic leakage. A granular appearance of the mucosa was identified in the area where the noncovered stent ends had adhered (●" Video 1). The patient had a favorable outcome and he is currently toleratingmost kinds of food. Anastomotic leakage of an esophagojejunal anastomosis after total gastrectomy is a severe complication associated with high mortality. In this situation, the use of self-expanding metal stents (SEMSs), fully or partially covered, has been reported to have a high stent-related adverse event rate [1–3]. Partially covered biodegradable stents could overcome some of the problems encountered with SEMSs. Their main advantage over SEMSs is that endoscopic removal is not needed. But up to the present time, the only commercially available biodegradable stents are uncovered or fully covered [1–5]. Fig.1 a Postoperative endoscopic view of the esophagojejunal anastomosis leakage in a 73-year-old man who underwent a total gastrectomy plus splenectomy for a gastric adenocarcinoma. b The customized, partially covered biodegradable stent. c Proximal noncovered end of the stent at 4 days after placement. d Also at 4 days, an endoscopic clip (Resolution; Boston Scientific, Natick, Massachusetts, United States) was applied at the upper border of the stent, as an antimigration measure. e At 2 months after placement, the noncovered distal end of the stent was adhering well to the wall of the jejunum. f At 6 weeks after stent placement, barium transit showed nonleakage of the lumen with resolution of the dehiscence.